Phenotype Image Detail

Image

Caption

Oat^tm1Dva/Oat^tm1Dva mice on an arginine-restricted diet (a) or a standard diet (b) at age 12 months. The large arrow heads indicate the basal infoldings of retinal pigment epithelium, healthy-appearing in (a) and virtually gone in (b). The small arrows indicate the apical processes of the retinal pigment epithelium, long and delicate in (a) and short and disorganized in (b). Abbreviations: choriocapillaris (CC); nuclei of the retinal pigment epithelium (N); melanosome (M); photoreceptor outer segment (OS); lipid droplets (L); glycogen accumulation (G)

Copyright

This image is from Wang T, Proc Natl Acad Sci U S A 2000 Feb 1;97(3):1224-9. Copyright 2000 National Academy of Sciences, U.S.A. J:60200

Associated Alleles

Symbol	Name
Oat^tm1Dva	ornithine aminotransferase; targeted mutation 1, David Valle

Associated Genotypes

Allelic Composition	Genetic Background
Oat^tm1Dva/Oat^tm1Dva	involves: 129S7/SvEvBrd