Phenotype Image Detail

Image

Caption

A & B: Dorsal root ganglions of wild-type (A) and Ttpa^tm1Hsz/Ttpa^tm1Hsz mice (B) stained with toluidine blue. Fine granular deposits of lipofuscin were present in ganglion cells in the homozygous mice. C & D: Retinal sections of wild-type (C) and homozygous mice (D). Autofluorescence (green signal in D) was detected in the outer segment of photoreceptor cells (OS) and retinal pigmentary epithelium (RPE). Scalebar A-B: 50um

Copyright

This image is from Yokota T, Proc Natl Acad Sci U S A 2001 Dec 18;98(26):15185-90. Copyright 2001 National Academy of Sciences, U.S.A. J:90006

Associated Alleles

Symbol	Name
Ttpa^tm1Hsz	tocopherol (alpha) transfer protein; targeted mutation 1, Hiroshi Suzuki

Associated Genotypes

Allelic Composition	Genetic Background
Ttpa^tm1Hsz/Ttpa^tm1Hsz	involves: 129S7/SvEvBrd * C57BL/6J