Phenotype Image Detail

Image

Caption

A & B: Verebral bone marrow, hematoxylin/eosin stained. Marrow from a P17 Sod2^tm1Leb/Sod2^tm1Leb mouse (A) is depleted of hematopoietic cells compared with marrow from a control mouse (B). C & D: Periodic acid/Schiff base stained hepatic glycogen from homozygous mutant mice (C) is coarsely granular (arrow) with a tendency toward centrilobular accumulation. In contrast, hepatic glycogen from control mice (D) is finely and evenly distributed within the hepatic lobule. E & F: Oil red O-stained neutral lipid within hepatocytes is increased substantially in homozygous mice (E) as compared with controls (F). Magnification: A & B: x60; C-F: x120

Copyright

This image is from Lebovitz RM, Proc Natl Acad Sci U S A 1996 Sep 3;93(18):9782-7. Copyright 1996 National Academy of Sciences, U.S.A. J:36148

Associated Alleles

Symbol	Name
Sod2^tm1Leb	superoxide dismutase 2, mitochondrial; targeted mutation 1, Russell M Lebovitz

Associated Genotypes

Allelic Composition	Genetic Background
Sod2^tm1Leb/Sod2^tm1Leb	B6.129S7-Sod2^tm1Leb/J