Phenotype Image Detail

Image

Caption

A: Bright-field view of a hemotoxylin and eosin stained histological section from an approximately 3 month old Aprt^tm1Jat/Aprt^tm1Jat male mouse. Note the large, rosette-shaped, brown-yellow crystals. B: Dark field view of A; visualized with a polarized light source. C: Bright field view of another histological section from the kidney of the same male mouse in A. Note the accumulation of stones in the renal pelvis. D: Dark field view of section in C, visualized with a polar light source. Magnification x94

Copyright

This image is from Engle SJ, Proc Natl Acad Sci U S A 1996 May 28;93(11):5307-12. Copyright 1996 National Academy of Sciences, U.S.A. J:33255

Associated Alleles

Symbol	Name
Aprt^tm1Jat	adenine phosphoribosyl transferase; targeted mutation 1, Jay A Tischfield

Associated Genotypes

Allelic Composition	Genetic Background
Aprt^tm1Jat/Aprt^tm1Jat	involves: 129S2/SvPas * Black Swiss