Phenotype Image Detail

Image

Caption

Sections of distal femoral growth plates from 12 week old wild type and Mmp13^tm1Smk/Mmp13^tm1Smk mice. Brackets indicate the approximate lengths of the growth plates. Higher-magnification views of the boxed areas in Left are shown in Right. Note the increased lengths of the growth plates and the irregular arrangement of the chondrocyte columns in the homozygous mutant samples in comparison to the wild type samples. Scale bar: 300um

Copyright

This image is from Inada M, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17192-7. Copyright 2004 National Academy of Sciences, U.S.A. J:94723

Associated Alleles

Symbol	Name
Mmp13^tm1Smk	matrix metallopeptidase 13; targeted mutation 1, Stephen M Krane

Associated Genotypes

Allelic Composition	Genetic Background
Mmp13^tm1Smk/Mmp13^tm1Smk	involves: 129S4/SvJae * C57BL/6