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Caption | Histological analysis of placentae from 12.5 dpc embryos. A: Placenta from wild type embryo stained with hematoxylin and eosin. Formation of decidua, trophoblast giant cell (arrowheads), spongiotrophoblast, and labyrinthine layers was normal. B: Placenta from EgfrWa5/+ embryo with reduced Sp and formation of multinucleated trophoblast cells (arrows). C: Placenta from phenotypically normal EgfrWa5/EgfrWa5 embryo with reduced Sp layer. D: Placenta from severely growth retarded EgfrWa5/EgfrWa5 embryo. The embryo attached to this placenta was 70% smaller than wild type littermates. Formation of multinucleated trophoblast cells, a highly disorganized Lt layer, and blood pockets were observed. Abbreviations: decidua (De); spongiotrophoblast (Sp); labyrinthine (Lt). Scale bar: 50um | ||||||
Copyright | This image is from Lee D, Mamm Genome 2004 Jul;15(7):525-36 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:92308 | ||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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