Phenotype Image Detail

Image

Caption

A: Increased numbers of normal-appearing macrophages were observed by 2 weeks of age in Sftpd^tm1Jhf/Sftpd^tm1Jhf mice. B: Enlarged, foamy, alveolar macrophages were readily observed by 3 weeks of age. C: By 6 weeks of age, multiple foci of large, foamy, alveolar macrophages were observed throughout the lungs. Scale bar 30um

Copyright

This image is from Wert SE, Proc Natl Acad Sci U S A 2000 May 23;97(11):5972-7. Copyright 2000 National Academy of Sciences, U.S.A. J:62282

Associated Alleles

Symbol	Name
Sftpd^tm1Jhf	surfactant associated protein D; targeted mutation 1, James H Fisher

Associated Genotypes

Allelic Composition	Genetic Background
Sftpd^tm1Jhf/Sftpd^tm1Jhf	involves: 129P2/OlaHsd * Black Swiss