Phenotype Image Detail

Image

Caption

Staining for alkaline phosphatase activity (brown) of E11.5 wild type (A) and Tial1^tm1Mst/Tial1^tm1Mst (B) gonads and E13.5 wild type (C) and homozygous mutant mouse (D) gonads. The mucosal lining of the embryonic stomach lumen in the upper left corner of each panel also shows alkaline phosphatase activity. The number of alkaline phosphatase staining cells seen is representative of two wild type and nine mutant E11.5 embryos. Sectioning of four entire mutant E11.5 embryos and staining for alkaline phosphatase activity did not reveal any ectopic alkaline phosphatase staining cells.

Copyright

This image is from Beck ARP, Proc Natl Acad Sci U S A 1998 Mar 3;95(5):2331-6. Copyright 1998 National Academy of Sciences, U.S.A. J:46239

Associated Alleles

Symbol	Name
Tial1^tm1Mst	Tia1 cytotoxic granule-associated RNA binding protein-like 1; targeted mutation 1, Michel Streuli

Associated Genotypes

Allelic Composition	Genetic Background
Tial1^tm1Mst/Tial1^tm1Mst	involves: 129S2/SvPas * C57BL/6