Phenotype Image Detail

Image

Caption

Representative histological sections of decalcified femurs from 7 month old wild type (A) and Col1a2^oim/Col1a2^oim mice (B). These demonstrate marked cortical thinning and fewer and thinner trabeculae in the diaphyseal region and femoral head of the homozygous mutant mouse. Magnification: x10

Copyright

This image is from Chipman SD, Proc Natl Acad Sci U S A 1993 Mar 1;90(5):1701-5. Copyright 1993 National Academy of Sciences, U.S.A. J:4348

Associated Alleles

Symbol	Name
Col1a2^oim	collagen, type I, alpha 2; osteogenesis imperfecta

Associated Genotypes

Allelic Composition	Genetic Background
Col1a2^oim/Col1a2^oim	involves: C3H/HeJ * C57BL/6JLe