Phenotype Image Detail

Image

Caption

A: Socs1^tm1Wehi/Socs1^tm1Wehi and littermate mice at 10 days of age showing retarded growth of the homozygous mutant mouse. Normal histological appearance of the liver (C), pancreas (E), and heart (G) of littermate mice is in contrast to the fatty degeneration of the liver (D); and monocytic infiltration of the pancreas (F) and heart (H) of the homozygous mutant mice.

Copyright

This image is from Starr R, Proc Natl Acad Sci U S A 1998 Nov 24;95(24):14395-9. Copyright 1998 National Academy of Sciences, U.S.A. J:51281

Associated Alleles

Symbol	Name
Socs1^tm1Wehi	suppressor of cytokine signaling 1; targeted mutation 1, Walter and Eliza Hall Institute of Medical Research

Associated Genotypes

Allelic Composition	Genetic Background
Socs1^tm1Wehi/Socs1^tm1Wehi	involves: 129S1/Sv * C57BL/6