Phenotype Image Detail

Image

Caption

Light microscopy shows retinas of 15 day old (A), 30 day old (B) and 90 day old (C) wild type (left), Rho^tm1Jlem/Rho⁺ (center), and Rho^tm1Jlem/Rho^tm1Jlem (right) littermate mice. D: Electron micrographs were prepared from the same tissue blocks used for light microscopy. The arrow indicates abnormally oriented membranes. Arrowheads point to outer segments in the homozygous mutant retina. Abbreviations: inner nuclear layer (INL); outer nuclear layer (ONL); inner segments (IS); outer segments (OS); retinal pigment epithelium (RPE) Scale bars: A-C: 20um; D: 200um and 1um

Copyright

This image is from Lem J, Proc Natl Acad Sci U S A 1999 Jan 19;96(2):736-41. Copyright 1999 National Academy of Sciences, U.S.A. J:52281

Associated Alleles

Symbol	Name
Rho^tm1Jlem	rhodopsin; targeted mutation 1, Janis Lem

Associated Genotypes

Allelic Composition	Genetic Background
Rho^tm1Jlem/Rho^tm1Jlem	involves: 129S4/SvJae
Rho^tm1Jlem/Rho^+	involves: 129S4/SvJae