Phenotype Image Detail

Image

Caption

Histological analysis of Apoe^shl/Apoe^shl mice. A & B: Paraffin-or cryo-section of a xanthomatous lesion stained with hematoxylin-eosin (a) or oil-red O (b). Note the numerous numbers of cholesterol cleft. Note a number of oil-red O stained cells, which include foam cells. C & D: Cross sections of aortic valves stained with Mason-trichrome (c) and oil-red O (d). Note the atherosclerotic lesions with cholesterol-clefts in the aortic wall.

Copyright

This image is from Matsushima Y, Mamm Genome 1999 Apr;10(4):352-7 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:54051

Associated Alleles

Symbol	Name
Apoe^shl	apolipoprotein E; spontaneous hyperlipidemia

Associated Genotypes

Allelic Composition	Genetic Background
Apoe^shl/Apoe^shl	involves: C3H/He * KOR
Apoe^shl/Apoe^shl	involves: BALB/c * KOR
Apoe^shl/Apoe^shl	involves: C57BL/6 * KOR