Phenotype Image Detail

Image

Caption

Maf^tm1Glm/Maf⁺ and Maf^tm1Glm/Maf^tm1Glm adult, neonatal, and embryonic lens. Richardson staining of homozygous mouse lens and heterozygous mouse lens at E12, E14, E16, postnatal day zero (P0), and 5 week old adults. Loss of c-maf- results in failure of posterior fiber elongation, apparent by E12, with subsequent absence of lens formation. Sections (1um) of Epon plastic embedded material were stained with Richardson stain.

Copyright

This image is from Kim JI, Proc Natl Acad Sci U S A 1999 Mar 30;96(7):3781-5. Copyright 1999 National Academy of Sciences, U.S.A. J:54079

Associated Alleles

Symbol	Name
Maf^tm1Glm	MAF bZIP transcription factor; targeted mutation 1, Laurie H Glimcher

Associated Genotypes

Allelic Composition	Genetic Background
Maf^tm1Glm/Maf^tm1Glm	involves: 129/Sv * BALB/c