Phenotype Image Detail

Image

Caption

Kif3a^tm1Gsn/Kif3a^tm1Gsn(-/-) embryos lack cilia on cells in the node. A-C: Scanning electron microscopy of 7.5PC embryos; arrows identify the node. D-F: High magnification view of nodes. Note the presence of cilia in the wild type node (D, astericks) and complete absence from homozygous mutant nodes (E & F). Scale bar: 5um

Copyright

This image is from Marszalek JR, Proc Natl Acad Sci U S A 1999 Apr 27;96(9):5043-8. Copyright 1999 National Academy of Sciences, U.S.A. J:54575

Associated Alleles

Symbol	Name
Kif3a^tm1Gsn	kinesin family member 3A; targeted mutation 1, Lawrence SB Goldstein

Associated Genotypes

Allelic Composition	Genetic Background
Kif3a^tm1Gsn/Kif3a^tm1Gsn	involves: 129S1/Sv * 129X1/SvJ