Phenotype Image Detail

Image

Caption

A: Survey of the fundus, deomstrating a layer of cyst-like elevations in the inner retina. B: Optical magnification reveals that the densely packed structures are clearly demarcated from the surrounding normal appearing regions. C: Focus on the retinal surface shows superficial vessels and the nerve fiber layer. Visible in the lower right quadrant are several larger cysts, one displacing a retinal vessel (arrow). D: Fundus photograph of a patient with RS, featuring typical small macular cysts arranged in a stellate pattern (arrow) and radial striae centered on the fovea. There is obvious similiarity to the appearance of the mouse retina as shown in B.

Copyright

This image is from Weber BH, Proc Natl Acad Sci U S A 2002 Apr 30;99(9):6222-7. Copyright 2002 National Academy of Sciences, U.S.A. J:76332

Associated Alleles

Symbol	Name
Rs1^tm1Web	retinoschisis (X-linked, juvenile) 1 (human); targeted mutation 1, Bernhard H F Weber

Associated Genotypes

Allelic Composition	Genetic Background
Rs1^tm1Web/Y	involves: 129S1/Sv * C57BL/6