Image |
|
||||||
Caption | A-F: Electron microscopy of the retina of wild type and Rs1tm1Web/Y mice at 2 months of age. (A) In the retina of wild type mice, typical ribbon synapses are present at the photoreceptor terminals (black arrows). (B) In the retina of hemizygous mice, increased extracellular spaces (open arrow) are observed in regions of ribbon synapses (solid arrow). Larger extracellular gaps are present between individual photoreceptor terminals (asterisk). (C) The extracellular gaps (asterisk) in the INL of hemizygous mice are filled with cellular debris (solid arrows) and membranous whorls (open arrow). (D) Part of the extracellular debris in the INL gaps (asterisk) of hemizygous mice consists of fragmented nerve cell terminals (solid arrow) containing synaptic vesicles. (E) Cells with ultrastructural characteristics of microglia in the retina of hemizygous mice. In the increased extracellular spaces, cells with long cytoplasmic processes (arrows) are observed. (F) Upon higher magnification, multiple clear vesicles (solid arrow) and electron-dense phagolysosomes (open arrow) are observed in the cytoplasm of the cells. Scale bars: A, B, D, & F: 0.53um; C & E: 1.4um | ||||||
Copyright | This image is from Weber BH, Proc Natl Acad Sci U S A 2002 Apr 30;99(9):6222-7. Copyright 2002 National Academy of Sciences, U.S.A. J:76332 | ||||||
Associated Alleles |
|
||||||
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
![]() |
|