Phenotype Image Detail

Image

Caption

A & B: Abnormal external appearance of Traf6^tm1Jino/Traf6^tm1Jino mice (right). C: Appearance of homozygous mice (lower) and Traf6^tm1Jino/Traf6⁺ (upper) at day 1. Homozygous mutant mice have more translucent skin then their heterozygous littermates. D & E: Flat mount sections of back skin of homozygous mice and their heterozygous littermates, respectively at day 1. Note that small unpigmented hair follicles (clear small spots) are present even in the back skin of homozygous mice.

Copyright

This image is from Naito A, Proc Natl Acad Sci U S A 2002 Jun 25;99(13):8766-71. Copyright 2002 National Academy of Sciences, U.S.A. J:77350

Associated Alleles

Symbol	Name
Traf6^tm1Jino	TNF receptor-associated factor 6; targeted mutation 1, Jun-ichiro Inoue

Associated Genotypes

Allelic Composition	Genetic Background
Traf6^tm1Jino/Traf6^tm1Jino	involves: 129P2/OlaHsd * C57BL/6