Phenotype Image Detail

Image

Caption

A: Reduced ovary size and thread-like uterus in Kiss1^tm1Coll/Kiss1^tm1Coll mice. B & C: Histology of ovaries showing larger number of atretic follicles (arrows) in homozygous mutant mice (C) and absence of late-stage follicle maturation (F) present in wild type mice. D & E: Histology of uterus showing full development of glands (arrows) in the endometrial layer in wild type (D) in contrast to mutant mice (E). Abbreviation: uterine lumen (L). Scale bars: A: 1mm; B & C: 100um; D & E: 25um

Copyright

This image is from d'Anglemont de Tassigny X, Proc Natl Acad Sci U S A 2007 Jun 19;104(25):10714-9. Copyright 2007 National Academy of Sciences, U.S.A. J:122381

Associated Alleles

Symbol	Name
Kiss1^tm1Coll	KiSS-1 metastasis-suppressor; targeted mutation 1, William H Colledge

Associated Genotypes

Allelic Composition	Genetic Background
Kiss1^tm1Coll/Kiss1^tm1Coll	involves: 129S/SvEv * 129S6/SvEvTac