Phenotype Image Detail

Image

Caption

A: An 8 month old Ereg^tm1Sawa/Ereg^tm1Sawa mouse with chronic dermatitis around the face. B-D: Chronic dermatitis in skin of homozygous mutant mice. Comparison sections of skin wild type (left) and mutant mice (right) were stained with hematoxylin and eosin (B), toluidine blue staining for mast cells (C), and Luna staining for eosinophils (D).

Copyright

This image is from Shirasawa S, Proc Natl Acad Sci U S A 2004 Sep 21;101(38):13921-6. Copyright 2004 National Academy of Sciences, U.S.A. J:92618

Associated Alleles

Symbol	Name
Ereg^tm1Sawa	epiregulin; targeted mutation 1, Senji Shirasawa

Associated Genotypes

Allelic Composition	Genetic Background
Ereg^tm1Sawa/Ereg^tm1Sawa	involves: 129X1/SvJ * C57BL/6J