Phenotype Image Detail

Image

Caption

A-D: Medial views of paintfilled wild type and Jag1^Mhdahtu/Jag1⁺ inner ears at E16.5. B: The phenotype where both ampullae are absent. D: The phenotype in which just the posterior is missing. Asterisks in B and D indicate the positions of the missing ampullae. Note the smaller anterior ampulla in the heterozygous mutant (arrow in D). E & F: Scanning electron microscopy of the anterior crista in the wild type and mutant mouse at P3. Note the small, flat appearance and the missing eminentia cruciata (arrow in E) in the mutant crista (F). Abbreviations: aa: anterior ampulla; asc: anterior semicular canal; cd: cochlear duct; la: lateral ampulla; lsc: lateral semicircular canal; pa: posterior ampulla; psc: posterior semicircular canal; ut: utricle Scale barL A-D: 500um; E & F: 100um

Copyright

This image is from Kiernan AE, Proc Natl Acad Sci U S A 2001 Mar 27;98(7):3873-8. Copyright 2001 National Academy of Sciences, U.S.A. J:72108

Associated Alleles

Symbol	Name
Jag1^Mhdahtu	jagged 1; Martin Hrabe de Angelis headturner

Associated Genotypes

Allelic Composition	Genetic Background
Jag1^Mhdahtu/Jag1^+	C3HeB/FeJ-Jag1^Mhdahtu