Phenotype Image Detail

Image

Caption

White matter (hippocampal fimbria) sections of a control (A) and Arsa^tm1Gie/Arsa^tm1Gie mouse (B) stained for sulfatide with alcian blue. No staining is detected in the brain of the control mouse. White matter of the deficient mouse displays cells filled with large storage granules and linearly arranged small cellular process with small granules. C: Ultrastructure of storage material. Prismatic herringbone-like inclusions in an astrocyte of a mutant mouse. Scale bar 100um

Copyright

This image is from Hess B, Proc Natl Acad Sci U S A 1996 Dec 10;93(25):14821-6. Copyright 1996 National Academy of Sciences, U.S.A. J:37978

Associated Alleles

Symbol	Name
Arsa^tm1Gie	arylsulfatase A; targeted mutation 1, Volkmar Gieselmann

Associated Genotypes

Allelic Composition	Genetic Background
Arsa^tm1Gie/Arsa^tm1Gie	involves: 129P2/OlaHsd * C57BL/6J