Phenotype Image Detail

Image

Caption

A: Whole-mount immunohistochemistry of an E16.5 Slit3^tm1Dor/Slit3^tm1Dor mouse diaphragm using the MF-20 (antimyosin) antibody. The arrow indicates a defect in the central tendon, and the arrowhead indicates a defect in diaphragm muscle. B & C: Frontal sections of E14.5 wild type and homozygous mutant embryos showing the thickness of the anterior central tendon (between arrows).

Copyright

This image is from Yuan W, Proc Natl Acad Sci U S A 2003 Apr 29;100(9):5217-22. Copyright 2003 National Academy of Sciences, U.S.A. J:83292

Associated Alleles

Symbol	Name
Slit3^tm1Dor	slit guidance ligand 3; targeted mutation 1, David M Ornitz

Associated Genotypes

Allelic Composition	Genetic Background
Slit3^tm1Dor/Slit3^tm1Dor	involves: 129S1/Sv * C57BL/6J