Phenotype Image Detail

Image

Caption

Electron microscopic analysis shows a variable but extensive loss of thin filaments within the sarcomeres along with myofilament disarry in the heart of the newborn Actc1^tm1Jll/Actc1^tm1Jll mouse (lower) in comparison to the newborn wild type mouse (upper).

Copyright

This image is from Kumar A, Proc Natl Acad Sci U S A 1997 Apr 29;94(9):4406-11. Copyright 1997 National Academy of Sciences, U.S.A. J:40165

Associated Alleles

Symbol	Name
Actc1^tm1Jll	actin, alpha, cardiac muscle 1; targeted mutation 1, James Lessard

Associated Genotypes

Allelic Composition	Genetic Background
Actc1^tm1Jll/Actc1^tm1Jll	involves: 129P2/OlaHsd * Black Swiss