Phenotype Image Detail

Image

Caption

A: Mapk8^tm1Flv/Mapk8^tm1Flv Mapk9^tm1Flv/Mapk9⁺ pups are pale in color and have open eyes at birth, compared with control littermates. B: H & E stained sections of E18.5 eyes indicate that mutant embryos are born with open eyes. L, lens; EL, eyelid. C: Adult mutant mice have opaque eyes.

Copyright

This image is from Weston CR, Proc Natl Acad Sci U S A 2004 Oct 28;101(39):14114-9. Copyright 2004 National Academy of Sciences, U.S.A. J:93433

Associated Alleles

Symbol	Name
Mapk8^tm1Flv	mitogen-activated protein kinase 8; targeted mutation 1, Richard Flavell
Mapk9^tm1Flv	mitogen-activated protein kinase 9; targeted mutation 1, Richard Flavell

Associated Genotypes

Allelic Composition	Genetic Background
Mapk8^tm1Flv/Mapk8^tm1Flv Mapk9^tm1Flv/Mapk9^+	B6.129S-Mapk9^tm1Flv Mapk8^tm1Flv