Phenotype Image Detail

Image

Caption

A: Hematoxylin/eosin stained sections of testes from wild type (left) and Spem1^tm1Wyan/Spem1^tm1Wyan (right) mice. Both show robust spematogenesis, B: Phase-contrast microscopic analyses of wild type and homozygous mutant epididymal sperm. Note that cytoplasmic droplets (CD's) (arrows) are present in the middle piece or the junction between the middle and principal pieces of athe tail in wild type epididymal sperm, whereas mutant mouse epididymal sperm show no CD's. C: Hematoxylin/eosin stained sperm smear preparations. (center and right) Mutant mouse sperm display deformation with heads bent backward pointing to tail tips (arrows) or bent heads wrapped around by necks and middle pieces of the tails (arrowheads). Scale bars: A: 50um; B: 20um; C: 10um

Copyright

This image is from Zheng H, Proc Natl Acad Sci U S A 2007 Apr 17;104(16):6852-7. Copyright 2007 National Academy of Sciences, U.S.A. J:120937

Associated Alleles

Symbol	Name
Spem1^tm1Wyan	spermatid maturation 1; targeted mutation 1, Wei Yan

Associated Genotypes

Allelic Composition	Genetic Background
Spem1^tm1Wyan/Spem1^tm1Wyan	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J