Phenotype Image Detail

Image

Caption

B-J: The appearance of control and Ubr1^tm1Avar/Ubr1^tm1Avar Ubr2^tm1Ytkw/Ubr2^tm1Ytkw mouse embryos at E9.5 (B-D), E10.5 (E-G) and E11.5 (H-J). Markings are as follows: arrow, heart; asterisk, swollen pericardial sac; arrowhead, a hemorrhage. Scale bar: 1mm

Copyright

This image is from An JY, Proc Natl Acad Sci U S A 2006 Apr 18;103(16):6212-7. Copyright 2006 National Academy of Sciences, U.S.A. J:109036

Associated Alleles

Symbol	Name
Ubr1^tm1Avar	ubiquitin protein ligase E3 component n-recognin 1; targeted mutation 1, Alexander Varshavsky
Ubr2^tm1Ytkw	ubiquitin protein ligase E3 component n-recognin 2; targeted mutation 1, Yong Tae Kwon

Associated Genotypes

Allelic Composition	Genetic Background
Ubr1^tm1Avar/Ubr1^tm1Avar Ubr2^tm1Ytkw/Ubr2^tm1Ytkw	involves: 129S1/Sv * C57BL/6