Phenotype Image Detail

Image

Caption

Wild type (C3H top row) and Tcm/Tcm (bottom row). Homozygous mouse phenotype is first observed at 10.5 dpc as a delay in optic cup formation. The lens pit is present at 10.5 dpc and a vestige lens remains at 13.5 dpc. By 13.5 dpc the dorsal retina appears developed with both the neural and pigmented retina layers recognizable but abnormally disassociated (pigmented epithelilum flanked by arrows). In contrast, no ventral retina structures are visible. Retina and lens dysplasia is prominent by 14.5 dpc.

Copyright

This image is from Wang KS, Mamm Genome 2005 May;16(5):332-43 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:100636

Associated Alleles

Symbol	Name
Tcm	total cataract with microphthalmia

Associated Genotypes

Allelic Composition	Genetic Background
Tcm/Tcm	involves: 101 * 102 * C3H