Phenotype Image Detail

Image

Caption

The lumbar spinal cord central canal is nearly obliterated in the wild type embryo (E) at E18.5, whereas the Nfia^tm1Rmg/Nfia^tm1Rmg embryo (F) shows persistent dilation of the lumbar spinal cord central canal (syringomyella, arrow).

Copyright

This image is from Lu W, PLoS Genet 2007 May 25;3(5):e80, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122749

Associated Alleles

Symbol	Name
Nfia^tm1Rmg	nuclear factor I/A; targeted mutation 1, Richard M Gronostajski

Associated Genotypes

Allelic Composition	Genetic Background
Nfia^tm1Rmg/Nfia^tm1Rmg	involves: 129P2/OlaHsd * C57BL/6