Phenotype Image Detail

Image

Caption

G: Normal wild type newborn renal histology. H-K: Nfia^tm1Rmg/Nfia^tm1Rmg renal histology. H-I: Homozygotes show an elongated, partial duplex kidney with the abnormal cortical zone that demarcates the two poles shown with an arrow. J: Severely dysplastic kidney with disorganized renal parenchyma. K: Renal tubule cystic dilatation.

Copyright

This image is from Lu W, PLoS Genet 2007 May 25;3(5):e80, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122749

Associated Alleles

Symbol	Name
Nfia^tm1Rmg	nuclear factor I/A; targeted mutation 1, Richard M Gronostajski

Associated Genotypes

Allelic Composition	Genetic Background
Nfia^tm1Rmg/Nfia^tm1Rmg	involves: 129P2/OlaHsd * C57BL/6