Phenotype Image Detail

Image

Caption

Embryonic day 9.5 and 10.5 Gatad2a^tm1Rnu/Gatad2a^tm1Rnu embryos. Mutant embryos, significantly smaller, are shown in comparison with wild type littermates. Abnormalities in homozygous mutant embryos around day 9.5 ( A & B) include malformed and non-fused neural folds, failure of closure of anterior neuropore, missing or excessively large blood vessels in the yolk sac. Day 10.5 embryos (C & D) are disintegrating due to multiple defects.

Copyright

This image is from Marino S, PLoS ONE 2007;2(6):e519, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:126871

Associated Alleles

Symbol	Name
Gatad2a^tm1Rnu	GATA zinc finger domain containing 2A; targeted mutation 1, Roel Nusse

Associated Genotypes

Allelic Composition	Genetic Background
Gatad2a^tm1Rnu/Gatad2a^tm1Rnu	involves: 129S1/Sv * 129X1/SvJ * C57BL/6