Phenotype Image Detail

Image

Caption

A-E: P13 normal mouse thymus. F-K: P13 Apc^tm2Rak/Apc^tm2Rak Tg(KRT14-cre)8Brn/0 mutant mouse thymus. Stained with K8 (A,D,F,I), K1 (B,E,G,J) and incolucrin (C,H,K). Note the lack of incolucrin staining in normal thymus but varying degree of positive cells in the mutant thymus. Scale Bars: A-C, F-H, J-K: 100um; D-E & I: 20um

Copyright

This image is from Kuraguchi M, PLoS Genet 2006;2(9):e146, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:114152

Associated Alleles

Symbol	Name
Apc^tm2Rak	APC, WNT signaling pathway regulator; targeted mutation 2, Raju Kucherlapati
Tg(KRT14-cre)8Brn	transgene insertion 8, Anton Berns

Associated Genotypes

Allelic Composition	Genetic Background
Apc^tm2Rak/Apc^tm2Rak Tg(KRT14-cre)8Brn/0	involves: 129/Sv * C57BL/6J * FVB/N * SJL