Phenotype Image Detail

Image

Caption

A: Representative T1-weighted axial (A upper) and coronal (A lower) MRI demonstrating enlarged lateral (asterisk) and third (arrowhead) ventricles in 3 to 6.5 month old Bbs1^tm1Vcs/Bbs1^tm1Vcs vs. wild type mice. B: Quantification of ventricular volumes from MRI data using ImageJ software. C: Neutral red-stained 100um thick coronal brain sections from mice used in the MRI study illustrate enlarged lateral and third ventricles, thinning of the cerebral cortex (CC), reduced hippocampus (H), and corpus striatum (S). Scale bars: 1mm

Copyright

This image is from Davis RE, Proc Natl Acad Sci U S A 2007 Dec 4;104(49):19422-7. Copyright 2007 National Academy of Sciences, U.S.A. J:128532

Associated Alleles

Symbol	Name
Bbs1^tm1Vcs	Bardet-Biedl syndrome 1; targeted mutation 1, Val C Sheffield

Associated Genotypes

Allelic Composition	Genetic Background
Bbs1^tm1Vcs/Bbs1^tm1Vcs	involves: 129S1/Sv * 129X1/SvJ