Phenotype Image Detail

Image

Caption

C: The 14 day old Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs mouse (right) displays a strikingly attenuated growth compared to its Xpa^tm1Hvs/Xpa^tm1Hvs littermate (left). F: Comparison of the 18.5 day old double homozygous (right) and homozygous littermate (left) embryo indicates the growth defect is postnatal.

Copyright

This image is from van der Pluijm I, PLoS Biol 2006 Dec 12;5(1):e2, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122013

Associated Alleles

Symbol	Name
Ercc6^tm1Gvh	excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst
Xpa^tm1Hvs	xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg

Associated Genotypes

Allelic Composition	Genetic Background
Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs	involves: 129P2/OlaHsd * C57BL/6J