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Caption | A: E18.5 Pygo1tm1.1Ssp/Pygo1tm1.1Ssp Pygo2tm1.2Ssp/Pygo2+ embryos, with only one wild type Pygo2 allele, appear normal. B & C: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp Pygo2tm1.2Ssp/Pygo2tm1.2Ssp embryos were smaller, with eye defects including absent or rudimentary lens and folded pigmented retina (arrows). (C) A small percentage of double homozygous embryos display exencephaly. | ||||||
Copyright | This image is from Schwab KR, BMC Biol 2007;5():15, an open-access article, licensee BioMed Central Ltd. J:121918 | ||||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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