Phenotype Image Detail

Image

Caption

Shown are wild type (A), Cubn^tm1Sarg/Cubn⁺ (B) and Cubn^tm1Sarg/Cubn^tm1Sarg 8-8.5dpc embryos (C-E). Embryos in A & B have been dissected to lie in a planar configuration where as embryos in C-D are intact. F & G: Hematoxylin and eosin stained sections of 8.5 dpc wild type (F) and mutant (G) embryos. Mutant 8.5 dpc embryos possess an allantois and amnion, but lack somites. Abbreviations: A, allantois; Am, amnion; S, somite. Scale bars A-G: 100um

Copyright

This image is from Smith BT, BMC Dev Biol 2006;6():30, an open-access article, licensee BioMed Central Ltd. J:119685

Associated Alleles

Symbol	Name
Cubn^tm1Sarg	cubilin; targeted mutation 1, Scott Argraves

Associated Genotypes

Allelic Composition	Genetic Background
Cubn^tm1Sarg/Cubn^tm1Sarg	involves: 129/Sv * C57BL/6