Phenotype Image Detail

Image

Caption

A: At E9.75 wild type and Mapk7^tm1Jsca/Mapk7^tm1Jsca yolk sacs contain blood islands (arrow). By E10.25 (B), the blood vessels found in wild type yolk sacs formed distinct large vessels which branched down into smaller vessels (arrow). In contrast, the surfaces of the mutant yolk sacs became pale, and did not show the branched blood vessels. At. E11.5 (C), mutant yolk sacs appeared intermittent with diffuse patches of red blood cells (arrow). The mutant embryos are pale and apparently devoid of blood circulation without a beating heart.

Copyright

This image is from Yan L, BMC Dev Biol 2003 Dec 16;3():11, an open-access article, licensee BioMed Central Ltd. J:107620

Associated Alleles

Symbol	Name
Mapk7^tm1Jsca	mitogen-activated protein kinase 7; targeted mutation 1, J Simon C Arthur

Associated Genotypes

Allelic Composition	Genetic Background
Mapk7^tm1Jsca/Mapk7^tm1Jsca	either: (involves: BALB/c) or (involves: C57BL/6)