Phenotype Image Detail

Image

Caption

Embryos were stained using a CD31 antibody. At E9.75 (A) networks of large blood vessels were seen in the head regions of both wild type and Mapk7^tm1Jsca/Mapk7^tm1Jsca embryos (red arrow), and intersomitic vessels (blue arrow), were also apparent in both genotypes. By E10.25 however the blood vessels in the head region of wild type embryos had started to undergo angiogenesis to give rise to branched networks of smaller vessels. This was not seen in the mutant embryos (compare red arrows in B). Similarly more branching was seen in the intersomitic vessels in wild type than mutant embryos at E10.25 (blue arrows).

Copyright

This image is from Yan L, BMC Dev Biol 2003 Dec 16;3():11, an open-access article, licensee BioMed Central Ltd. J:107620

Associated Alleles

Symbol	Name
Mapk7^tm1Jsca	mitogen-activated protein kinase 7; targeted mutation 1, J Simon C Arthur

Associated Genotypes

Allelic Composition	Genetic Background
Mapk7^tm1Jsca/Mapk7^tm1Jsca	either: (involves: BALB/c) or (involves: C57BL/6)