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Phenotype Image Detail
Image
Caption Ultrastructure of skin lesions from Tg(rv-CYCLIN)29Dlh/0 mice. A & B: Skin sections from tail lesions from transgenic mouse illustrating pleomorphic epithelium with prominent tonofilaments, interdigitating plasma membrane extensions (A), and large irregular nucleolar morphology (B). Cells with features of apoptotic cell death (small compact nuclei with dark condensed nuclear chromatin indicated by arrow in A). C: Basement membranes (black arrow) disrupted by cytoplasmic extensions of epithelial cells (white arrow) from tail lesions from transgenic mice. D: Nests of epithelial cells in a whorl pattern convoluted nuclei from tail skin lesions of transgenic line 150.
Copyright This image is from Lairmore MD, Proc Natl Acad Sci U S A 2000 May 23;97(11):6114-9. Copyright 2000 National Academy of Sciences, U.S.A. J:62478
Associated
Alleles
Symbol Name
Tg(rv-CYCLIN)29Dlh transgene insertion 29, Donald L Holzschu
Associated
Genotypes
Allelic Composition Genetic Background
Tg(rv-CYCLIN)29Dlh/0 involves: C57BL/6 * SJL

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory