Phenotype Image Detail

Image

Caption

A: Wild type and Srf^tm2.1Nor/Srf^tm2.1Nor Tg(Ckmm-cre)5Khn/0 (Srf^flex1/flex1/MCK-Cre) mice at P3 are shown. The mutant is severely runted. C: Histological sections of representative muscle groups of wild-type and mutant mice stained with hematoxylin and eosin. The cross-sectional area of the muscle fibers in the mutant is smaller than that of the wild-type. Scale bar: 20um

Copyright

This image is from Li S, Proc Natl Acad Sci U S A 2005 Jan 25;102(4):1082-7. Copyright 2005 National Academy of Sciences, U.S.A. J:96122

Associated Alleles

Symbol	Name
Srf^tm2.1Nor	serum response factor; targeted mutation 2.1, Alfred Nordheim
Tg(Ckmm-cre)5Khn	transgene insertion 5, C Ronald Kahn

Associated Genotypes

Allelic Composition	Genetic Background
Srf^tm2.1Nor/Srf^tm2.1Nor Tg(Ckmm-cre)5Khn/0	involves: 129P2/OlaHsd * C57BL/6