Phenotype Image Detail

Image

Caption

Compared to controls, the Gt(ROSA)26Sor^tm1(Wnt4)Bhr/Gt(ROSA)26Sor⁺ Tg(Col2a1-cre)1Bhr/0 mice have a smaller skeleton, abnormal skulls with a domed vault (arrowhead) and protruding incisors (small arrow). Kyphosis (large arrow) of the cervical thoracic spine is also seen in the mutants.

Copyright

This image is from Lee HH, PLoS ONE 2007;2(5):e450, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:129327

Associated Alleles

Symbol	Name
Gt(ROSA)26Sor^tm1(Wnt4)Bhr	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Richard R Behringer
Tg(Col2a1-cre)1Bhr	transgene insertion 1, Richard R Behringer

Associated Genotypes

Allelic Composition	Genetic Background
Gt(ROSA)26Sor^tm1(Wnt4)Bhr/Gt(ROSA)26Sor^+ Tg(Col2a1-cre)1Bhr/0	involves: 129S7/SvEvBrd * C57BL/6 * SJL