Phenotype Image Detail

Image

Caption

A: Representative image of Sulf1^{Gt(OST352220)Lex}/Sulf1^{Gt(OST352220)Lex} Sulf2^{Gt(OST311938)Lex}/Sulf2^{Gt(OST311938)Lex} (right) and littermate control (left) E18.5 day embryos just after birth, but prior to feeding. Note the pink skin tone and apparently normal vascularization and circulation. C: Representative image of a typical small 10 week old double homozygous male (lower) and littermate control (upper). Note the proportionate small stature and the lack of gross morphological differences. E: Kidneys of mutant mice (lower) were small at E18.5 and remain disproportionately small into adulthood.

Copyright

This image is from Holst CR, PLoS ONE 2007;2(6):e575, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:129305

Associated Alleles

Symbol	Name
Sulf1^Gt(OST352220)Lex	sulfatase 1; gene trap OST352220, Lexicon Genetics
Sulf1^Gt(OST352220)Lex	sulfatase 1; gene trap OST352220, Lexicon Genetics
Sulf2^Gt(OST311938)Lex	sulfatase 2; gene trap OST311938, Lexicon Genetics
Sulf2^Gt(OST311938)Lex	sulfatase 2; gene trap OST311938, Lexicon Genetics

Associated Genotypes

Allelic Composition	Genetic Background
Sulf1^Gt(OST352220)Lex/Sulf1^Gt(OST352220)Lex Sulf2^Gt(OST311938)Lex/Sulf2^Gt(OST311938)Lex	involves: 129S5/SvEvBrd * C57BL/6N