Phenotype Image Detail

Image

Caption

Transmission electron microscopy (TEM) of the untrastructure (x6,000) of outer segment (OS) in the wild type and Rp1^tm1Jnz/Rp1^tm1Jnz mouse retinas at one month of age. Cross section (x50,000) of connecting cilia of mutant mouse retina appears normal (Inset). Disoriented discs (arrowhead), whorls, and disk membranes (arrows) of abnormal sizes were found in the mutant retina.

Copyright

This image is from Gao J, Proc Natl Acad Sci U S A 2002 Apr 16;99(8):5698-703. Copyright 2002 National Academy of Sciences, U.S.A. J:76071

Associated Alleles

Symbol	Name
Rp1^tm1Jnz	retinitis pigmentosa 1 (human); targeted mutation 1, Jian Zuo

Associated Genotypes

Allelic Composition	Genetic Background
Rp1^tm1Jnz/Rp1^tm1Jnz	involves: 129S7/SvEvBrd
Rp1^tm1Jnz/Rp1^tm1Jnz	involves: 129S7/SvEvBrd * C57BL/6