Phenotype Image Detail

Image

Caption

A & C: Localization of Ptx3 expression in the ventral midbrain (arrow) of wild type neonate. B & D: Ptx3 staining is almost depleted in the Nr4a2^tm1Omc/Nr4a2^tm1Omc midbrain. TUNEL staining in the ventral midbrain region of wild type (E) and mutant mice (F). Notice the increase in TUNEL positive nuclei (arrowheads) and dying cells (asterisk) in the mutant mice. Scale bar: 20um

Copyright

This image is from Saucedo-Cardenas O, Proc Natl Acad Sci U S A 1998 Mar 31;95(7):4013-8. Copyright 1998 National Academy of Sciences, U.S.A. J:46856

Associated Alleles

Symbol	Name
Nr4a2^tm1Omc	nuclear receptor subfamily 4, group A, member 2; targeted mutation 1, Orla M Conneely

Associated Genotypes

Allelic Composition	Genetic Background
Nr4a2^tm1Omc/Nr4a2^tm1Omc	involves: 129S7/SvEvBrd * C57BL/6