Phenotype Image Detail

Image

Caption

Preserved clinical condition of Hexb^tm1Rlp/Hexb^tm1Rlp mice deficient for Ccl3 (MIP-1alpha) was clearly noted at 4 months of age compared to littermates. Hexb^tm1Rlp/Hexb^tm1Rlp and Hexb^tm1Rlp/Hexb^tm1Rlp Ccl3^tm1Unc/Ccl3^tm1Unc mice are shown.

Copyright

This image is from Wu YP, Proc Natl Acad Sci U S A 2004 Jun 1;101(22):8425-30. Copyright 2004 National Academy of Sciences, U.S.A. J:90687

Associated Alleles

Symbol	Name
Ccl3^tm1Unc	C-C motif chemokine ligand 3; targeted mutation 1, University of North Carolina
Hexb^tm1Rlp	hexosaminidase B; targeted mutation 1, Richard L Proia

Associated Genotypes

Allelic Composition	Genetic Background
Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Ccl3^tm1Unc/Ccl3^tm1Unc Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6