Phenotype Image Detail

Image

Caption

Bladder cancer specimens from wild type (A,B) and Mif^tm1Dvd/Mif^tm1Dvd(C,D) mice treated with N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN). A and C are representative areas of tumor with (A) and without (C) muscle invasion. B and D show immunohistochemical staining for vascular structures (arrowheads) by PECAM-1 in the same region. Note the marked increase in number of vessels in the wild type (B) compared to the mutant mouse (D).

Copyright

This image is from Taylor JA rd, BMC Cancer 2007;7():135, an open-access article, licensee BioMed Central Ltd. J:126543

Associated Alleles

Symbol	Name
Mif^tm1Dvd	macrophage migration inhibitory factor (glycosylation-inhibiting factor); targeted mutation 1, John R David

Associated Genotypes

Allelic Composition	Genetic Background
Mif^tm1Dvd/Mif^tm1Dvd	B6.129S4-Mif^tm1Dvd