Phenotype Image Detail

Image

Caption

A: Representative photograph demonstrating the appearance of livers from fasted wild type (left) and Ppara^tm1Gonz/Ppara^tm1Gonz (right) mice. The livers were harvested rapidly from age-matched wild type and mutant mice after a 24 hour fast. The left hepatic lobes are shown. B: Photomicrographs demonstrating the histologic appearance of the livers of mutant mice under fed and fasted conditions. Frozen tissue sections were prepared from the livers of mutant mice after a 24 hour fast (Fasted) and age-matched controls fed ad libitum (Fed). The sections were stained with oil red O. The red droplets indicate positive staining for neutral lipid.

Copyright

This image is from Leone TC, Proc Natl Acad Sci U S A 1999 Jun 22;96(13):7473-8. Copyright 1999 National Academy of Sciences, U.S.A. J:56056

Associated Alleles

Symbol	Name
Ppara^tm1Gonz	peroxisome proliferator activated receptor alpha; targeted mutation 1, Frank J Gonzalez

Associated Genotypes

Allelic Composition	Genetic Background
Ppara^tm1Gonz/Ppara^tm1Gonz	129S4/SvJae-Ppara^tm1Gonz