Phenotype Image Detail

Image

Caption

A: Newborn wild type submandibular gland (SMB). B: Newborn Fgfr2^tm1.1Dsn/Fgfr2⁺ SMG. C: Newborn wild type SMG. D: Newborn Fgf10^tm1Ska/Fgf10⁺ SMG. Wild type mice (A & C) exhibit Late Terminal Bud Stage SMGs consisting of ducts and terminal buds displaying distinct lumina. In contrast, fewer ducts and terminal buds are seen in B & D heterozygous mutant SMGs. Scalebar, 50um.

Copyright

This image is from Jaskoll T, BMC Dev Biol 2005;5():11, an open-access article, licensee BioMed Central Ltd. J:119849

Associated Alleles

Symbol	Name
Fgf10^tm1Ska	fibroblast growth factor 10; targeted mutation 1, Shigeaki Kato
Fgfr2^tm1.1Dsn	fibroblast growth factor receptor 2; targeted mutation 1.1, Clive Dickson

Associated Genotypes

Allelic Composition	Genetic Background
Fgfr2^tm1.1Dsn/Fgfr2^+	involves: 129P2/OlaHsd * C57BL/6
Fgf10^tm1Ska/Fgf10^+	involves: C57BL/6 * CBA