Phenotype Image Detail

Image

Caption

Hematoxylin and eosin stained sections are shown from ZS+NMBA-treated (zinc sufficient N-nitrosomethylbenzylamine, A-D) and ZD+NMBA-treated (zinc deficient N-nitrosomethylbenzylamine, E-H) mice. ZS+NMBA-treated mice: papillomas in wild type (A) and Tes^tm1Cro/Tes⁺ (B) mice are shown, as are atypical glandular metaplasia (C) and squamous carcinoma (E) in Tes^tm1Cro/Tes^tm1Cro mice. ZD+NMBA-treated mice: a papilloma in a wild type mouse is shown, as are atypical glandular metaplasia and invasive adenocarcinomas in heterozygous (F) and homozygous (G) mice and squamous cell carcinoma in a homozygous (H) mouse. Scale bar, 100mm.

Copyright

This image is from Drusco A, Proc Natl Acad Sci U S A 2005 Aug 2;102(31):10947-51. Copyright 2005 National Academy of Sciences, U.S.A. J:100181

Associated Alleles

Symbol	Name
Tes^tm1Cro	testin LIM domain protein; targeted mutation 1, Carlo M Croce

Associated Genotypes

Allelic Composition	Genetic Background
Tes^tm1Cro/Tes^tm1Cro	involves: 129X1/SvJ * C57BL/6J
Tes^tm1Cro/Tes^+	involves: 129X1/SvJ * C57BL/6J