Phenotype Image Detail

Image

Caption

A-D: Appearance of a 3 week old (A), and a 7 week old (B) Tg(KRT14-Tslp)1Pcn/0 mouse, with closer views of the ears shown in Insets. Photos of skin lesions exhibited by the 7 week old mouse in the neck (C) and on dorsal (D) regions were taken after shaving. White arrowheads point to lesioned skin. E-F: Hematoxylin and eosin stained ear sections of 3 week old control (E) and transgenic (F) mice. White arrows point to the dermal/epidermal junction. Yellow arrow points to blood vessel. hf, hair follicle. G-H: Immunohistochemical staining of CD4 on ear sections from 3 week old control (G) and transgenic (H) mice. Red color corresponds to the staining of antibodies, and blue corresponds to the DAPI staining of nuclei. White arrows point to dermal/epidermal junction. Scale bar: 50um.

Copyright

This image is from Li M, Proc Natl Acad Sci U S A 2005 Oct 11;102(41):14795-800. Copyright 2005 National Academy of Sciences, U.S.A. J:102470

Associated Alleles

Symbol	Name
Tg(KRT14-Tslp)1Pcn	transgene insertion 1, Pierre Chambon

Associated Genotypes

Allelic Composition	Genetic Background
Tg(KRT14-Tslp)1Pcn/0	involves: C57BL/6 * SJL