Phenotype Image Detail

Image

Caption

A: Mortality in C1galt1^ptl1/C1galt1^ptl1 and C1galt1^ptl1/C1galt1^ptl1 Rag1^tm1Bal/Rag1^tm1Bal mice. B: Histological sections of kidneys from sick C1galt1^ptl1/C1galt1^ptl1 or C1galt1^ptl1/C1galt1^ptl1 Rag1^tm1Bal/Rag1^tm1Bal mice and healthy controls illustrating the extensive inflammatory infiltration, loss of glomeruli, and tubular disorganization in the C1galt1^ptl1/C1galt1^ptl1 mouse kidneys.

Copyright

This image is from Alexander WS, Proc Natl Acad Sci U S A 2006 Oct 31;103(44):16442-7. Copyright 2006 National Academy of Sciences, U.S.A. J:115272

Associated Alleles

Symbol	Name
C1galt1^ptl1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; ptl1
Rag1^tm1Bal	recombination activating 1; targeted mutation 1, David Baltimore

Associated Genotypes

Allelic Composition	Genetic Background
C1galt1^ptl1/C1galt1^ptl1	C57BL/6-C1galt1^ptl1
C1galt1^ptl1/C1galt1^ptl1 Rag1^tm1Bal/Rag1^tm1Bal	involves: 129S4/SvJae * C57BL/6